Jonathan J Lyons Selected Research

Tryptases (Tryptase)

4/2022	Hereditary alpha-tryptasemia modifies clinical phenotypes among individuals with congenital hypermobility disorders.
1/2022	Incorporating Tryptase Genotyping Into the Workup and Diagnosis of Mast Cell Diseases and Reactions.
1/2022	Proposed European Competence Network on Mastocytosis-American Initiative in Mast Cell Diseases (ECNM-AIM) Response Criteria in Advanced Systemic Mastocytosis.
1/2022	Hereditary alpha-tryptasemia despite normal tryptase-encoding gene copy number owing to copy number loss in trans.
1/2022	Defining baseline variability of serum tryptase levels improves accuracy in identifying anaphylaxis.
1/2022	Elevated Basal Serum Tryptase: Disease Distribution and Variability in a Regional Health System.
1/2022	Resolving the genetics of human tryptases: implications for health, disease, and clinical use as a biomarker.
12/2021	Clinical relevance of inherited genetic differences in human tryptases: Hereditary alpha-tryptasemia and beyond.
11/2021	Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal.
10/2021	Inherited and acquired determinants of serum tryptase levels in humans.

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Jonathan J Lyons Research Topics

Disease

15	Hereditary alpha-tryptasemia syndrome 04/2022 - 01/2018
10	Anaphylaxis (Anaphylactic Shock) 01/2022 - 05/2013
6	Mastocytosis 01/2022 - 01/2019
5	Hypersensitivity (Allergy) 01/2022 - 05/2013
5	Mast Cell Activation Disorders (Mast-Cell Disease) 01/2022 - 11/2019
5	Immediate Hypersensitivity 01/2022 - 01/2016
4	Neoplasms (Cancer) 01/2022 - 01/2019
3	Inflammation (Inflammations) 10/2021 - 01/2016
3	Mast Cell Activation Syndrome 01/2021 - 01/2019
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2022 - 01/2015
2	Systemic Mastocytosis 01/2022 - 01/2021
2	Atopic Dermatitis (Atopic Eczema) 01/2021 - 08/2017
2	Lymphopenia (Lymphocytopenia) 01/2021 - 01/2021
2	Autonomic Nervous System Diseases (Dysautonomia) 10/2019 - 12/2016
2	Joint Instability (Joint Laxity) 01/2017 - 12/2016
1	Chronic Renal Insufficiency 01/2022
1	Asthma (Bronchial Asthma) 01/2022
1	Rheumatoid Arthritis 01/2022
1	Eosinophilic Esophagitis 01/2022
1	Hematologic Neoplasms (Hematological Malignancy) 01/2022
1	Cutaneous Mastocytosis 01/2021
1	Crohn Disease (Crohn's Disease) 01/2021
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2021
1	Dermatitis 01/2021
1	Chronic Inducible Urticaria 10/2019
1	Gaucher Disease (Gaucher's Disease) 03/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 09/2017
1	Infections 08/2017
1	Measles 01/2017
1	Optic Atrophy 01/2017
1	Rubella (German Measles) 01/2017
1	Cone Dystrophy 01/2017
1	Flushing 12/2016
1	Chronic Pain 12/2016
1	Pruritus (Itching) 12/2016
1	Wiskott-Aldrich Syndrome 10/2016
1	Food Hypersensitivity (Food Allergy) 01/2016
1	Job Syndrome (Hyper-IgE Syndrome) 01/2016
1	Eosinophilia 02/2015
1	Aplastic Anemia (Anemia, Hypoplastic) 01/2015

Drug/Important Bio-Agent (IBA)

26	Tryptases (Tryptase)IBA 04/2022 - 12/2016
7	Immunoglobulin E (IgE)IBA 01/2022 - 02/2015
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2016
2	Biological ProductsIBA 01/2022 - 01/2021
2	VenomsIBA 01/2021 - 10/2020
2	Arthropod VenomsIBA 01/2021 - 10/2020
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2016 - 01/2015
1	Protein Isoforms (Isoforms)IBA 01/2022
1	NucleotidesIBA 01/2021
1	MitogensIBA 01/2021
1	AntibodiesIBA 01/2021
1	Immunoglobulin G (IgG)IBA 01/2021
1	CytokinesIBA 09/2017
1	AlbuminsIBA 01/2017
1	Retinaldehyde (Retinal)IBA 01/2017
1	AllergensIBA 10/2016
1	Histamine Receptors (Histamine Receptor)IBA 01/2016
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2016
1	Transcription Factors (Transcription Factor)IBA 01/2015
1	Filgrastim (Neupogen)FDA Link 05/2013

Therapy/Procedure

2	Therapeutics 01/2022 - 01/2018
1	Hematopoietic Stem Cell Transplantation 01/2016